In a world where high performance often overshadows inner peace, Isabel Rössle is leading a transformative global movement that brings ancient wisdom, cutting-edge neuroscience, and modern wellness under one holistic umbrella. A German-Chilean psychologist, entrepreneur, and former international model, Isabel’s remarkable evolution from the fashion industry to the forefront of psychedelic healing and longevity innovation represents a bold new blueprint for leadership and legacy.
From Modelling Fame to Meaningful Mission
Isabel’s early years were spent between Germany and Chile, where she developed a deep connection to spirituality and psychology — a duality that would later define her path. While she did not personally struggle with clinical depression, her adolescence was marked by the emotional challenges of navigating two very different cultures. The internal conflict of adapting to German cultural expectations after her Latin American upbringing fueled a deep desire to explore healing modalities. Her discovery of plant medicine, especially the use of magic mushrooms, proved instrumental in addressing this cultural trauma and expanding her personal awareness.
After 17 successful years in international modelling, Isabel made a conscious pivot toward deeper purpose, trading photo shoots for meditation retreats and haute couture for holistic transformation. She founded Chez Zen, a retreat center nestled in the peaceful countryside of Gascony, South of France. Chez Zen quickly became a destination for academics, high-performers, and seekers alike, offering trauma-informed therapies, tantra, breathwork, and spiritual growth experiences.
The Rise of Psychedelic Leadership
During the COVID-19 pandemic, Isabel relocated to Mexico, drawn by its cultural openness and legal flexibility for alternative therapies. There, she launched Mexico-Retreats.com, expanding her practice to include psychedelic-assisted therapy. With a focus on clinical safety, ethics, and trauma-sensitive frameworks, Isabel introduced legal substances such as psilocybin and MDMA into her programs — observing transformative effects on emotional trauma and anxiety.
In collaboration with celebrated speaker and medical doctor Dr. Stefan Frädrich, Isabel co-founded Reality Upgrade Retreats, hosting immersive psychedelic retreats in the Netherlands and Mexico. These experiences integrate ancient ceremony with modern tools — yoga, breathwork, cold exposure, nature immersion, and group therapy — and are further enhanced by traditional sweat lodges (temazcal), and even sensual dance, offering participants a profound, multi-sensory journey of transformation.
Iconic Leadership Summit & Global Recognition
Reality Upgrade’s work extends beyond retreats. Isabel and Dr. Frädrich also host the Iconic Leadership Summit on Richard Branson’s Necker Island — a highly curated gathering designed to cultivate visionary thinking, conscious entrepreneurship, and deep personal evolution. The summit unites global pioneers across industries through shared experiences of healing, reflection, and purpose.
Shaping the Future: Training & Longevity Innovation
As demand for trained facilitators in the psychedelic field continues to rise, Isabel has launched a specialized Apprenticeship Program under the Reality Upgrade banner. This initiative equips future psychedelic leaders with rigorous scientific knowledge, spiritual grounding, and trauma-informed practices to ensure ethical facilitation in a sensitive, fast-growing space.
Looking ahead, Isabel is entering the longevity and biohacking space with bold ambition. Alongside Dr. Frädrich and a world-class biohacking expert, she is developing a new line of wellness products designed to reverse aging, extend vitality, and optimize healthspan — blending ancient intelligence with biomedical innovation.
A Philosophy Rooted in Authenticity
Throughout her journey, Isabel has remained guided by one core principle: “Don’t be a missionary. Be an inspiration.” Her work is not about persuasion — it’s about being a beacon for those ready to awaken, evolve, and lead with heart.
Through her platforms — @pia_isabel_int and @reality_upgrade_retreat — Isabel Rössle continues to bridge science, soul, and success in a way few leaders can. As psychedelic healing earns global legitimacy and longevity innovation paves the next frontier of human potential, Isabel is not just participating in the wellness revolution — she is helping shape its very foundation.
👉 Learn more at psychedelic-leadership.com
